Fig. 9. Histopathology analysis of lung tissue in semi-acute model.
Balb/c mice were instilled once with either DM-only, MWCNT, or SiO2 at week 0, kept on the normal mouse chow for 1 week, and then put on either a control or 1% DHA diet for 3 weeks. (a) Pathology was scored blinded by two observers; data presented as median ± SEM. (b) Airway thickness was measured blinded; data presented as mean ± SEM. (c) Representative images (10x) of Masson’s trichrome-stained lung airway sections. n=3; **P<0.01 compared to DM. Arrows indicate particle encapsulation, blue staining indicates collagen deposition
