IC50's of lead aryl 2-AP analogues against panel of S. aureus strains biofilms.
Compound | MRSA 43300 (μM) | MRSA BAA-44 (μM) | MRSA 33591 (μM) | S. aureus 6538 (μM) |
---|---|---|---|---|
8e | 26.4 ± 4.9 | 29.5 ± 2.1 | 26.6 ± 4.1 | 24.9 ± 4.2 |
8g | 17.4 ± 6.4 | 14.1 ± 2.2 | 20.2 ± 3.0 | 15.6 ± 6.4 |