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. 2020 Dec 8;12(2):293–296. doi: 10.1039/d0md00238k

IC50's of lead aryl 2-AP analogues against panel of S. aureus strains biofilms.

Compound MRSA 43300 (μM) MRSA BAA-44 (μM) MRSA 33591 (μM) S. aureus 6538 (μM)
8e 26.4 ± 4.9 29.5 ± 2.1 26.6 ± 4.1 24.9 ± 4.2
8g 17.4 ± 6.4 14.1 ± 2.2 20.2 ± 3.0 15.6 ± 6.4