TABLE 4:

Comparison of the model evidence computation for the 2,3, and 4 state gene expression model using ST-MCMC with the full fidelity and Multifidelity ST-MCMC with β-tuning. The evidence estimates from the full-fidelity and multifidelity methods are consistent, but the multifidelity scheme is significantly faster.

Model	Full-fidelity		Tuned IT Bridge
	Log Evidence	Time (Sec)	Log Evidence	Time (Sec)
2 Gene	−20108.8 ± 5.4	1244	−20112.6 ± 2.0	758
3 Gene	−20111.9 ± 5.6	67496	−20115.7 ± 2.0	17511
4 Gene	−20113.0 ± 5.7	76546	−20117.5 ± 1.8	23777