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. 2021 May 13;35:20587384211016194. doi: 10.1177/20587384211016194

Table 1.

Effect of PIC on hepatic and renal mitochondrial redox status in rats exposed to RES or γ-radiation.

Parameters Control PIC RES RES + PIC IR IR + PIC
Hepatic oxidative stress status
MDA (nmol/g protein) 288 ± 16a 279 ± 13a 399 ± 29b 307 ± 24c 465 ± 21d 334 ± 29e
NO (nmol/g protein) 13.5 ± 2.6a 14.2 ± 1.4a 5.8 ± 1.2b 8.2 ± 1.8c 4.9 ± 0.9b 9.2 ± 0.7d
SOD (U/mg protein) 8.8 ± 0.8a 9.3 ± 0.6a 3.7 ± 0.9b 6.7 ± 1.8c 4.1 ± 1.2b 8.8 ± 0.5a
CAT (U/mg protein) 2.5 ± 0.4a 3.0 ± 0.3a 0.3 ± 0.03b 1.4 ± 0.2c 0.4 ± 0.07b 2.1 ± 0.3a
GSH-PX (U/mg protein) 21.2 ± 0.8 a 22.3 ± 0.8a 7.2 ± 1.1b 14.2 ± 0.7c 9.1 ± 0.5d 19.9 ± 1.1e
GR (U/g protein) 759 ± 13a 756 ± 10a 426 ± 14b 645 ± 19c 331 ± 15d 622 ± 18c
Renal oxidative stress status
MDA (nmol/g protein) 291 ± 32a 283 ± 22a 393 ± 28b 300 ± 31c 457 ± 19d 304 ± 30c
NO (nmol/g protein) 18.8 ± 0.6a 17.8 ± 1.2a 9.7 ± 1.6b 15.2 ± 0.6c 7.1 ± 0.4b 13.9 ± 1.3d
SOD (U/mg protein) 7.0 ± 0.6a 7.1 ± 2.3a 2.4 ± 1.1b 5.1 ± 3.6c 3.2 ± 1.9d 7.7 ± 3.0a
CAT (U/mg protein) 2.3 ± 0.4a 2.5 ± 0.5a 0.3 ± 0.2b 2.2 ± 0.2a 0.5 ± 0.2c 2.3 ± 0.8a
GPX (U/mg protein) 11.3 ± 1.2a 12.3 ± 1.4a 5.2 ± 0.8b 9.2 ± 0.7c 4.4 ± 0.3d 10.7 ±1.2a
GR (U/g protein) 164 ± 13a 160 ± 11a 72 ± 8b 105 ± 29c 65‎ ± 9b 139 ± 12a

Data are presented as means ± SD (n = 8). Groups with different letters are significantly different, at P ⩽ 0.05. Groups with similar letters are not significantly different, at P ⩽ 0.05.