. 2021 May 13;35:20587384211016194. doi: 10.1177/20587384211016194

Table 2.

Effect of PIC on inflammatory markers and hepatic and renal functions status in rats exposed to RES or γ-radiation.

Parameters	Control	PIC	RES	RES + PIC	IR	IR + PIC
Inflammatory markers
TNF-α (pg/mL serum)	26 ± 2^a	22 ± 4^a	125 ± 10^b	44 ± 6^c	121 ± 10^b	56 ± 12^d
IL-6 (pg/mL serum)	37 ± 4^a	35 ± 5^a	113 ± 30^b	43 ± 11^a	119 ± 16^b	57 ± 12^c
Hepatic functions
ALT (U/mL serum)	32 ± 5^a	31 ± 10^a	104 ± 8^b	49 ± 6^c	130 ± 19^d	71 ± 13^e
AST (U/L serum)	72 ± 9^a	70 ± 8^a	213 ± 5^b	90 ± 14^c	225 ± 18^d	105 ± 15^e
ALP (U/L serum)	110 ± 17^a	113 ± 12^a	164 ± 5^b	118 ± 7^a	159 ± 8^b	120 ± 6^c
Renal functions
Urea (mg/dL serum)	52 ± 5^a	49 ± 10^a	60 ± 8^b	37 ± 4^c	88 ± 12^d	55 ± 6^a
Creatinine (mg/dL serum)	0.66 ± 0.10^a	0.67 ± 0.15^a	0.90 ± 0.39^b	0.51 ± 0.25^c	0.78 ± 0.33^d	0.68 ± 0.36^a

Data are presented as means ± SD (n = 8). Groups with different letters are significantly different, at P ⩽ 0.05. Groups with similar letters are not significantly different, at P ⩽ 0.05.