Table 4.
Effect of PIC on hepatic and renal apoptotic markers in rats exposed to RES or γ-radiation.
| Parameters | Control | PIC | RES | RES + PIC | IR | IR + PIC |
|---|---|---|---|---|---|---|
| Hepatic apoptotic markers | ||||||
| Caspase-3 (ng/mg protein) | 11.0 ± 2.5a | 10.4 ± 1.8a | 39.8 ± 3.5b | 22.3 ± 7.5c | 37.6 ± 9.1d | 15.7 ± 7.1e |
| Cytochrome-c (ng/mg) | 0.82 ± 0.49a | 0.77 ± 0.43a | 4.78 ± 0.6b | 1.8 ± 0.22c | 4.93 ± 0.79d | 0.91 ± 0.18b |
| Renal apoptotic markers | ||||||
| Caspase-3 (ng/mg protein) | 2.3 ± 0.4a | 2.1 ± 0.5a | 9.2 ± 1.4b | 5.3 ± 0.9c | 8.4 ± 1.9d | 3.4 ± 0.5a |
| Cytochrome-c (ng/mg) | 0.62 ± 0.11a | 0.59 ± 0.15a | 4.03 ± 0.52b | 1.75 ± 0.75c | 2.56 ± 0.98d | 0.81 ± 0.06b |
Data are presented as means ± SD (n = 8). G\groups with different letters are significantly different, at P ⩽ 0.05. Groups with similar letters are not significantly different, at P ⩽ 0.05.