Table 1.

Univariate and multivariable analysis of disease free survival (DSS) and progression-free survival (PFS) in patients with renal cell carcinoma (RCC).

Feature	DSS
	Univariate		Multivariable
	HR (95%CI)	P value	HR (95%CI)	P value
Age
(>55.0 vs.≤55.0)	1.16 (0.50-2.69)	0.723	–	–
Sex
(male vs. female)	0.92 (0.36-2.37)	0.877	–	-
Clinical stage
(III/IV vs. I/II)	1.79 (1.11-2.87)	0.016	1.10 (074-2.29)	0863
Nucleolar grade
(III/IV vs. I/II)	3.38 (1.39-8.25)	0.007	2.57 (0.96-6.83)	0.058
Tumor size	1.16 (1.04-1.28)	0.005	1.13 (1.01-1.26)	0.034
Nuclear SMAD4 Expression
High vs. low	2.60 (1.09-6.21)	0.031	3.10 (1.26-7.61)	0.013

HR, hazard ratio; CI, confidence interval; MVI, microvascular invasion.

Values in bold are statistically significant.