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. Author manuscript; available in PMC: 2021 May 17.
Published in final edited form as: Cancer Res. 2018 Oct 9;78(24):6828–6837. doi: 10.1158/0008-5472.CAN-18-1654

Figure 1.

Figure 1.

Effect of SQAP on tumor cell and tissue growth inhibition by XRT. A, Structure of SQAP or CG-0321 (C27H51O10S1/2Ca, Mw 587.79). B, C, In vitro cell survival after various doses of XRT in the presence or absence of SQAP (10 μM). Effects on murine SCCVII (B) and human A549 (C). D–G, Growth kinetics of mice tumor xenografts and mice body weight (BW) changes after each treatment. D, C3H mice bearing murine SCCVII tumors. E, Athymic nude mice bearing human A549 tumors. F, G, BW changes in C3H mice (F) or athymic nude mice (G) in each treatment group. + signifies treatment. Data are means ± SE (SCCVII: n = 5, A549: n = 7–8). **, P < 0.01, ***, P < 0.001.