Table 4.
Repeated measures analysis of variance results for scores of HAMD17, HAMA, SDS, SAS, and AIS between cCBT + TAU group and TAU group at baseline, postintervention, and follow-up.
| Measure | cCBTa + TAUb group (n=51) | TAU group (n=50) | Difference (95% CI) | P valuec | Partial η2 | |
| HAMD17d | ||||||
|
|
Baseline, mean (SD) | 15.28 (2.23) | 15.70 (1.28) | –0.42 (–1.22 to 0.38) | .30 | 0.02 |
|
|
Postintervention, mean (SD) | 7.86 (3.04)e | 15.46 (1.76) | –7.60 (–8.61 to –6.60) | <.001 | 0.82 |
|
|
Follow-up, mean (SD) | 6.86 (1.77)e,f | 15.26 (2.32) | –8.40 (–9.30 to –7.50) | <.001 | 0.87 |
|
|
P value | <.001g | <.001h | <.001i | N/Aj | N/A |
| HAMAk | ||||||
|
|
Baseline, mean (SD) | 14.26 (2.31) | 13.88 (1.86) | 0.38 (–0.41 to 1.17) | .34 | 0.02 |
|
|
Postintervention, mean (SD) | 7.38 (2.84)e | 13.24 (2.26) | –5.86 (–6.83 to –4.89) | <.001 | 0.75 |
|
|
Follow-up, mean (SD) | 6.10 (2.04)e,f | 13.20 (1.96) | –7.10 (–7.81 to –6.39) | <.001 | 0.89 |
|
|
P value | <.001g | <.001h | <.001i | N/A | N/A |
| SDSl | ||||||
|
|
Baseline, mean (SD) | 46.10 (7.59) | 45.22 (8.15) | 0.88 (–2.48 to 4.24) | .60 | 0.01 |
|
|
Postintervention, mean (SD) | 32.56 (6.54)e | 45.56 (6.59) | –13.00 (–15.80 to –10.20) | <.001 | 0.64 |
|
|
Follow-up, mean (SD) | 31.14 (5.65)e,f | 44.70 (6.05) | –13.56 (–15.98 to –11.14) | <.001 | 0.72 |
|
|
P value | <.001g | <.001h | <.001i | N/A | N/A |
| SASm | ||||||
|
|
Baseline, mean (SD) | 44.30 (10.49) | 45.56 (7.25) | –1.26 (–4.97 to 2.45) | .50 | 0.01 |
|
|
Postintervention, mean (SD) | 29.66 (7.31)e | 45.52 (7.05) | –15.86 (–18.97 to –12.75) | <.001 | 0.68 |
|
|
Follow-up, mean (SD) | 29.12 (6.08)e | 44.92 (5.92) | –15.80 (–18.34 to –13.27) | <.001 | 0.76 |
|
|
P value | <.001g | <.001h | <.001i | N/A | N/A |
| AISn | ||||||
|
|
Baseline, mean (SD) | 8.58 (2.95) | 8.20 (1.29) | 0.38 (–0.51 to 1.27) | .40 | 0.02 |
|
|
Postintervention, mean (SD) | 6.98 (2.99)e | 8.00 (2.22) | –1.02 (–2.11 to 0.07) | .06 | 0.07 |
|
|
Follow-up, mean (SD) | 6.88 (2.72)e | 7.82 (2.17) | –0.94 (–1.84 to –0.04) | .04 | 0.08 |
|
|
P value | <.001g | <.001h | .002i | N/A | N/A |
acCBT: computerized cognitive behavioral therapy.
bTAU: treatment as usual.
cP value adjusted by the Bonferroni method of between-group differences.
dHAMD17: Hamilton Depression Rating Scale.
eCompared with baseline, P<.05, adjusted by the Bonferroni method.
fCompared with postintervention, P<.05, adjusted by the Bonferroni method.
gP value of group effect in the mixed-effects model for repeated measures.
hP value of time effect in the mixed-effects model for repeated measures.
iP value of interactive effects between time and group in the mixed-effects model for repeated measures.
jN/A: not applicable.
kHAMA: Hamilton Anxiety Scale.
lSDS: Self-Rating Depression Scale.
mSAS: Self-Rating Anxiety Scale.
nAIS: Athens Insomnia Scale.