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. Author manuscript; available in PMC: 2021 May 17.
Published in final edited form as: Science. 2020 Jun 26;368(6498):eaba3203. doi: 10.1126/science.aba3203

Figure 3. Visual axons are not required for NME and NMC specification but maintenance.

Figure 3.

(A) NMCs are observed associated with original visual axons but not with axons from transplanted eyes. Cartoon on left shows location of transplanted eyes. (B) NMEs/NMCs are present in uninjured animals with few or no visual axons (ovo RNAi). Right top: Density map shows NME/NMC distributions in an idealized visual system cartoon. n indicates number of animals mapped. Right bottom: Graph shows NME/NMC numbers in uninjured RNAi animals. Regeneration of NMEs (C) and NMEs/NMCs (D) in ovo RNAi animals after eye resection (C) or head amputation (D). Bottom left: Mapping shows NME/NMC distributions in an idealized visual system cartoon. n indicates number of animals mapped. Bottom right: Graph shows NME/NMC numbers. Red box shows location of image taken. Dark pink arrows or dots, NMEs; light pink arrows or dots, NMCs.

Scale bars, 100μm (A) and 50μm (B-D).