Figure 5.

B. dentium and γ-glutamylcysteine suppress TNBS colitis. a. Representative images of H&E stains of untreated control animals and TNBS treated animals receiving PBS vehicle, live B. dentium or γ-glutamylcysteine (scale bar = 100 µm). b. Histological scores of mice c. Serum cytokines heatmap as measured by Illumina Magpix. d-f. Colonic mRNA expression of ER-stress related genes (d) GRP-78, (D) CHOP and (f) sXBP1. All analyses were performed in untreated (n = 8), TNBS-PBS (n = 10), TNBS-B. dentium-treated (n = 10) or TNBS- γ-glutamylcysteine-treated mice (n = 8). *p < .05, One-Way ANOVA