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. 2021 May 17;16(5):e0251354. doi: 10.1371/journal.pone.0251354

Table 1. IC50 values calculated for different cancer cell lines with ADAADiN (at 24 and 48 hr) and ADAADiK (48 hr).

Cells IC50 (μM) for ADAADiN IC50 (μM) for ADAADiK
24 hr 48 hr 48 hr
A549 8.6 2.6 11.9
DU145 18.4 6.9 9.8
PC3 20.3 10.1 8.8
HepG2 9.2 4.8 12.6
HeLa 24.7 10.1 10.9
L132 19.5 11.3 686#
MCF-7 18.9 3.9# 379#
MDA-MB-231 Could not be calculated 37.9 11.9
HEK293 Could not be calculated 24.6 6.2#

Except #, all values were calculated using: https://www.aatbio.com/tools/ic50-calculator/.

# Calculated using quadratic equation.