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SIGN checklist for systematic review72
SIGN – Scottish Intercollegiate Guideline Network
aRating: “Yes” = 1, “No” or unable to tell from the article = 0
bScoring: Sum of items - >9 high quality, low risk of bias; 6–9 acceptable quality, moderate risk of bias; <6 low quality, high risk of bias; if 1 and/or 3 are “no” Unacceptable quality (reject)
