Modified SIGN Randomized controlled trial checklist74
SIGN – Scottish Intercollegiate Guideline Network
aRating: “Yes” = 1, “No” or unable to tell from the article = 0
bScoring: Sum of items - 9–10 high quality, low risk of bias; 6–8 acceptable quality, moderate risk of bias; 3–5 low quality, high risk of bias; 0–2 or if item 1 and/or 3 are “no” unacceptable quality (reject)