Study	Study design	Sample size	Description of study
Axelrod 1997	Case‐control	N = 18	Evaluates response to non‐invasive tests among 10 people with family dysautonomia and 8 healthy controls while supine and at 90 degrees tilt. Goal was to determine if autonomic dysfunction involves cardiac as well as peripheral vascular integrity. The participants with family dysautonomia were tested before and 1 hour after receiving oral fludrocortisone or midodrine.
Campbell 1976	Case series	N = 13	Describes long‐term follow‐up (mean 12 months) of 13 people receiving fludrocortisone for diabetic postural hypotension.
Chobanian 1979	Case series	N = 7	Describes effects of fludrocortisone among 7 people with orthostatic hypotension in terms of hypotension while in recumbent and standing positions.
Kochar 1978	Case series	N = 5	Describes effects of indomethacin in 5 people compared to either propranolol or fludrocortisone.
Matsubara 1990	Case series	N = 9	Describes effects of fludrocortisone in 9 people with Shy‐Drager syndrome when moving from supine to sitting up.
Pathak 2005a	Cohort	N = 121	Examines adverse drug reactions to drugs used in France for orthostatic hypotension, including fludrocortisone.
Pathak 2005a	Cohort	N = 31	Examines effects of heat on people with neurogenic orthostatic hypotension of varying etiologies, a subgroup of which received fludrocortisone.
Schatz 1976	Case series	N = 23	Describes response (satisfactory, excellent, good, fair, unsatisfactory) to fludrocortisone treatment among 23 people with orthostatic hypotension of varying etiologies (i.e. idiopathic, diabetes, Shy‐Drager, undifferentiated CNS disease, previous gastric surgery, amyloidosis).