Related to
Figure 6. (
A) BAT mass normalized to body mass. (
B) Gonadal white adipose tissue (gWAT) mass normalized to body mass. (
C) Inguinal white adipose tissue (iWAT) mass normalized to body mass. (
D) Liver triglyceride levels. (
E) mRNA expression of
Ucp1 in BAT normalized to
Gapdh. (
F) mRNA expression of
Ucp1 in iWAT. (
G) Representative immunoblot of tyrosine hydroxylase (TH) levels in iWAT of mice fed a HFD and densitometric quantification normalized by tubulin (images were cropped from the same membrane). (
H) Serum FGF21 level in WT and DKO mice. (
I) Serum FGF21 levels in WT and OPA1 BAT KO mice (KO). Data are expressed as means ± SEM. Significant differences were determined by two-way ANOVA, using a significance level of p<0.05. *Significantly different vs. WT control, #significantly different vs. WT HFD.