Table 1.
n | Quartile 1 | Quartile 2 | Quartile 3 | Quartile 4 | P-value | |
---|---|---|---|---|---|---|
WHI Ancillary Study | ||||||
EMPC | 1613 | 421 | 419 | 400 | 373 | <0.0001 |
BAA23 | 1914 | 524 | 483 | 459 | 448 | |
AS311 | 828 | 155 | 174 | 204 | 295 | |
Clinical trial participant | ||||||
Yes | 3536 | 926 | 918 | 861 | 831 | <0.0001 |
No | 819 | 163 | 170 | 228 | 258 | |
Case/control status (BAA23) | ||||||
Case | 948 | 267 | 234 | 239 | 208 | 0.01 |
Control | 966 | 254 | 254 | 225 | 233 | |
Case/control status (AS311) | ||||||
Case | 416 | 78 | 84 | 106 | 148 | <0.0001 |
Control | 412 | 77 | 91 | 109 | 135 | |
Study year | ||||||
Baseline | 4097 | 1039 | 1028 | 1019 | 1011 | 0.29 |
3 years | 163 | 31 | 37 | 46 | 49 | |
6 years | 95 | 19 | 23 | 24 | 29 | |
Age (years), mean (SD) | 64.0 (7.11) | 62.4 (7.1) | 64.1 (7.1) | 64.3 (7.0) | 65.1 (7.0) | <0.0001 |
Race/Ethnicity | ||||||
White | 2495 | 501 | 639 | 628 | 727 | <0.0001 |
African-American | 1076 | 369 | 261 | 252 | 194 | |
Hispanic/Latino | 610 | 190 | 153 | 157 | 110 | |
Asian or Pacific Islander | 105 | 8 | 18 | 27 | 52 | |
American Indian or Alaskan Native | 38 | 13 | 11 | 12 | 2 | |
Other | 30 | 8 | 6 | 12 | 4 | |
BMI (kg/m2) mean (SD) | 29.3 (6.1) | 30.8 (6.4) | 29.7 (6.2) | 29.0 (5.9) | 27.9 (5.5) | <0.0001 |
BMI categories | ||||||
Underweight | 23 | 2 | 5 | 10 | 6 | <0.0001 |
Normal | 1060 | 177 | 246 | 281 | 356 | |
Overweight | 1506 | 356 | 380 | 379 | 391 | |
Obese | 1735 | 544 | 449 | 411 | 331 | |
Smoking status | ||||||
Former and current | 2108 | 507 | 508 | 549 | 544 | 0.15 |
No | 2204 | 569 | 570 | 530 | 535 | |
Income | ||||||
<$20 000 | 1007 | 326 | 276 | 222 | 183 | <0.0001 |
$20 000–$49 999 | 1888 | 481 | 464 | 488 | 455 | |
>$50 000 | 1196 | 215 | 275 | 310 | 396 |