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. 2021 May 18;19:104. doi: 10.1186/s12915-021-01038-9

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — The Nematostella neuronal subtypes scale with changes in size. a,b Visualization of NvLWamide-like neurons in relation to body size during periods of feeding and starvation. Panels in a and b are each of a single individual. Arrows indicate longitudinal neurons and arrowheads indicate tripolar neurons. Oral end is to the left. Scale bar = 1 mm. c Increases and decreases animal length due to feeding and starvation, respectively. d Longitudinal neurons increase and decrease during periods of feeling and starvation, respectively. e Tripolar neurons increase and decrease following periods of feeding and starvation, respectively. c–e See Additional File 15: Table S5 for full model results (c F _2,34 = 25.75, p < 0.001, η_p² = 0.60; d F_2,36 = 77.35, p < 0.001, η_p² = 0.81; e tripolar, F_2,36 = 91.91, p < 0.001, η_p² = 0.84). Data points are means ± SEM, n = 10 animals per treatment, *p ≤ 0.05. Scale bar = 1 mm