Table 2.
Summary of the meta-analysis of associated factors for GDM.
No. | Factors | No. studies included | OR | 95% CI | I 2 | P heterogeneity | t | Bias P heterogeneity |
---|---|---|---|---|---|---|---|---|
1 | Maternal age ≥ 25 years | 36 | 2.466 | 2.121, 2.866 | 96.2 | <0.001 | 0.19 | 0.243 |
2 | Prepregnancy overweight or obese | 48 | 2.637 | 1.561, 4.453 | 99.8 | <0.001 | 4.85 | 0.001 |
3 | FHD | 74 | 2.326 | 1.904, 2.843 | 94.7 | <0.001 | 1.83 | 0.081 |
4 | Primigravida | 56 | 0.752 | 0.698, 0.810 | 94.7 | <0.001 | 1.53 | 0.132 |
5 | History of congenital anomaly | 3 | 1.837 | 0.418, 8.067 | 0.0 | 0.421 | — | — |
6 | History of GDM | 24 | 21.137 | 8.785, 50.858 | 96.9 | <0.001 | 1.35 | 0.181 |
7 | History of macrosomia | 26 | 2.539 | 1.612, 4.000 | 86.6 | <0.001 | 2.24 | 0.035 |
8 | HIV status | 4 | 1.168 | 0.902, 1.512 | 0.0 | 0.238 | — | — |
9 | History of stillbirth | 11 | 2.341 | 1.435, 3.819 | 52.0 | 0.001 | 0.18 | 0.862 |
10 | History of abortion | 19 | 1.546 | 0.906, 2.639 | 94.3 | 0.110 | 0.26 | 0.800 |
11 | History of premature delivery | 3 | 3.013 | 1.569, 5.787 | 0.0 | 0.001 | — | — |
12 | Pregestational smoking | 9 | 2.322 | 1.359, 3.967 | 66.7 | 0.002 | — | — |
CI: confidence interval; FHD: family history of diabetes mellitus; GDM: gestational diabetes mellitus; HIV: human immunodeficiency virus; OR: odds ratio.