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. 2021 May 10;2021:6692695. doi: 10.1155/2021/6692695

Table 2.

Summary of the meta-analysis of associated factors for GDM.

No. Factors No. studies included OR 95% CI I 2 P heterogeneity t Bias P heterogeneity
1 Maternal age ≥ 25 years 36 2.466 2.121, 2.866 96.2 <0.001 0.19 0.243
2 Prepregnancy overweight or obese 48 2.637 1.561, 4.453 99.8 <0.001 4.85 0.001
3 FHD 74 2.326 1.904, 2.843 94.7 <0.001 1.83 0.081
4 Primigravida 56 0.752 0.698, 0.810 94.7 <0.001 1.53 0.132
5 History of congenital anomaly 3 1.837 0.418, 8.067 0.0 0.421
6 History of GDM 24 21.137 8.785, 50.858 96.9 <0.001 1.35 0.181
7 History of macrosomia 26 2.539 1.612, 4.000 86.6 <0.001 2.24 0.035
8 HIV status 4 1.168 0.902, 1.512 0.0 0.238
9 History of stillbirth 11 2.341 1.435, 3.819 52.0 0.001 0.18 0.862
10 History of abortion 19 1.546 0.906, 2.639 94.3 0.110 0.26 0.800
11 History of premature delivery 3 3.013 1.569, 5.787 0.0 0.001
12 Pregestational smoking 9 2.322 1.359, 3.967 66.7 0.002

CI: confidence interval; FHD: family history of diabetes mellitus; GDM: gestational diabetes mellitus; HIV: human immunodeficiency virus; OR: odds ratio.