Table 2.
The connection information of shared genes.
| Genes | Description | Relationship | Score |
|---|---|---|---|
| SCN5A | Sodium voltage-gated channel alpha subunit 5 | Directly | 445.8 |
| KCNH2 | Potassium voltage-gated channel subfamily H member 2 | Directly | 409.76 |
| TNNT2 | Troponin T2, cardiac type | Directly | 293.82 |
| CALM1 | Calmodulin 1 | Directly | 222.12 |
| SCN4A | Sodium voltage-gated channel alpha subunit 4 | Directly | 158.41 |
| SCN10 A | Sodium voltage-gated channel alpha subunit 10 | Directly | 132.53 |
| ADRB1 | Adrenoceptor beta 1 | Directly | 97.00 |
| ADRB2 | Adrenoceptor beta 2 | Directly | 75.14 |
| CYP2C9 | Cytochrome P450 family 2 subfamily C member 9 | Directly | 53.13 |
| PDGFRB | Platelet-derived growth factor receptor beta | Directly | 46.86 |
| CHRM2 | Cholinergic receptor muscarinic 2 | Directly | 46.86 |
| MAPK1 | Mitogen-activated protein kinase 1 | Directly | 43.38 |
| EGFR | Epidermal growth factor receptor | Directly | 43.38 |
| ADRA1D | Adrenoceptor alpha 1D | Directly | 39.60 |
| ADRB3 | Adrenoceptor beta 3 | Directly | 39.60 |
| SCN9A | Sodium voltage-gated channel alpha subunit 9 | Directly | 35.42 |
| CYP3A4 | Cytochrome P450 family 3 subfamily A member 4 | Directly | 30.68 |
| CYP2D6 | Cytochrome P450 family 2 subfamily D member 6 | Directly | 25.05 |
| PON1 | Paraoxonase 1 | Directly | 25.05 |
| PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1 | Directly | 17.71 |
| CYP1A1 | Cytochrome P450 family 1 subfamily A member 1 | Directly | 17.71 |
| CHRM1 | Cholinergic receptor muscarinic 1 | Directly | 17.71 |
| CYP1A2 | Cytochrome P450 family 1 subfamily A member 2 | Directly | 17.71 |
| ADRA1A | Alpha-1A adrenergic receptor | Indirectly | 37.78 |
| ADRA1B | Alpha-1B adrenergic receptor | Indirectly | 36.23 |
| CHRM3 | Muscarinic acetylcholine receptor M3 | Indirectly | 28.09 |
| SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Indirectly | 13.50 |
| SLC47A1 | Multidrug and toxin extrusion protein 1 | Indirectly | 11.33 |
Notes: the score is an indication of the strength of the connection between the gene and the disease.