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. 2021 May 8;2021:5535480. doi: 10.1155/2021/5535480

Table 2.

The connection information of shared genes.

Genes Description Relationship Score
SCN5A Sodium voltage-gated channel alpha subunit 5 Directly 445.8
KCNH2 Potassium voltage-gated channel subfamily H member 2 Directly 409.76
TNNT2 Troponin T2, cardiac type Directly 293.82
CALM1 Calmodulin 1 Directly 222.12
SCN4A Sodium voltage-gated channel alpha subunit 4 Directly 158.41
SCN10 A Sodium voltage-gated channel alpha subunit 10 Directly 132.53
ADRB1 Adrenoceptor beta 1 Directly 97.00
ADRB2 Adrenoceptor beta 2 Directly 75.14
CYP2C9 Cytochrome P450 family 2 subfamily C member 9 Directly 53.13
PDGFRB Platelet-derived growth factor receptor beta Directly 46.86
CHRM2 Cholinergic receptor muscarinic 2 Directly 46.86
MAPK1 Mitogen-activated protein kinase 1 Directly 43.38
EGFR Epidermal growth factor receptor Directly 43.38
ADRA1D Adrenoceptor alpha 1D Directly 39.60
ADRB3 Adrenoceptor beta 3 Directly 39.60
SCN9A Sodium voltage-gated channel alpha subunit 9 Directly 35.42
CYP3A4 Cytochrome P450 family 3 subfamily A member 4 Directly 30.68
CYP2D6 Cytochrome P450 family 2 subfamily D member 6 Directly 25.05
PON1 Paraoxonase 1 Directly 25.05
PIK3R1 Phosphoinositide-3-kinase regulatory subunit 1 Directly 17.71
CYP1A1 Cytochrome P450 family 1 subfamily A member 1 Directly 17.71
CHRM1 Cholinergic receptor muscarinic 1 Directly 17.71
CYP1A2 Cytochrome P450 family 1 subfamily A member 2 Directly 17.71
ADRA1A Alpha-1A adrenergic receptor Indirectly 37.78
ADRA1B Alpha-1B adrenergic receptor Indirectly 36.23
CHRM3 Muscarinic acetylcholine receptor M3 Indirectly 28.09
SLCO1B1 Solute carrier organic anion transporter family member 1B1 Indirectly 13.50
SLC47A1 Multidrug and toxin extrusion protein 1 Indirectly 11.33

Notes: the score is an indication of the strength of the connection between the gene and the disease.