Table 3.

Diagnostic performance of the four readers regarding the MIBC detection for image set 1 and image set 2

	MIBC detection							Pairwise ROC curve comparison
	Sensitivity (95% CI)		Specificity (95% CI)		AUC set 1 (95% CI)	AUC set 2 (95% CI)	p value	Pairwise readers	p value set 1	p value set 2
	Set 1	Set 2	Set 1	Set 2
Reader 1	100.00 (59.04–100.00)	100.00 (59.04–100.00)	82.76 (64.23–94.16	83.33 (65.28–94.36)	0.91 (0.77–0.98)	0.92 (0.78–0.98)	0.99	Reader 1 vs reader 2 Reader 1 vs reader 3 Reader 1 vs reader 4 Reader 2 vs reader 3 Reader 2 vs reader 4 Reader 3 vs reader 4	0.66 0.42 0.99 0.17 0.57 0.42	0.57 0.66 0.32 0.99 0.57 0.71
Reader 2	100.00 (59.04–100.00)	100.00 (59.04–100.00)	79.31 (60.28–92.01)	79.31 (60.28–92.01)	0.90 (0.75–0.97)	0.90 (0.75–0.97)	0.99
Reader 3	100.00 (59.04–100.00)	100.00 (59.04–100.00)	89.66 (72.65–97.81)	79.31 (60.28–92.01)	0.95 (0.82–0.99)	0.90 (0.75–0.97)	0.07
Reader 4	100.00 (59.04–100.00)	100.00 (59.04–100.00)	80.00 (61.43–92.29)	74.19 (55.39–88.14)	0.90 (0.76–0.97)	0.87 (0.77–0.96)	0.15