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. 2021 Feb 13;58(6):2963–2973. doi: 10.1007/s12035-021-02322-z

Fig. 2.

Fig. 2

Etanercept (TNF-α inhibitor) prevents the development of heroin withdrawal-enhanced fear learning. Experimental timeline (a). Intra-DH etanercept infusions significantly attenuated enhanced fear learning (N = 31, n = 6-9) (b). Paxinos and Watson schematic with DH cannula placements shown. Each circle represents termination site of the cannula tract (c). *, statistically significant difference relative to respective control. Error bars indicate SEM