Table 2.
Secondary insults in relation to clinical outcome following aneurysmal subarachnoid hemorrhage—a temporal analysis of three phases the first 10 days
| Variables | Ictal phase | Early vasospasm phase | Late vasospasm phase | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Favorable | Unfavorable | p Value | Favorable | Unfavorable | p Value | Favorable | Unfavorable | p Value | |
| ICP > 20 mm Hg (%) | 3 (± 3) | 6 (± 9) | 0.001 | 3 (± 4) | 5 (± 13) | 0.04 | 2 (± 3) | 4 (± 12) | 0.01 |
| ICP > 25 mm Hg (%) | 1 (± 1) | 2 (± 2) | 0.001 | 1 (± 1) | 1 (± 3) | 0.30 | 1 (± 1) | 1 (± 4) | 0.35 |
| CPP < 60 mm Hg (%) | 4 (± 5) | 6 (± 7) | 0.09 | 2 (± 3) | 3 (± 4) | 0.01 | 1 (± 2) | 2 (± 5) | 0.02 |
| CPP < 70 mm Hg (%) | 26 (± 20) | 32 (± 19) | 0.05 | 14 (± 14) | 19 (± 17) | 0.05 | 8 (± 9) | 15 (± 17) | 0.001 |
| CPP < 80 mm Hg (%) | 59 (± 24) | 66 (± 21) | 0.04 | 41 (± 27) | 48 (± 26) | 0.06 | 27 (± 21) | 40 (± 27) | 0.001 |
| CPP < 90 mm Hg (%) | 84 (± 15) | 87 (± 14) | 0.08 | 69 (± 27) | 75 (± 23) | 0.09 | 55 (± 27) | 69 (± 25) | 0.001 |
| ∆CPPopt < -10 mm Hg (%) | 25 (± 14) | 25 (± 13) | 0.94 | 18 (± 12) | 20 (± 12) | 0.44 | 18 (± 11) | 20 (± 11) | 0.19 |
| ∆CPPopt ± 10 mm Hg (%) | 55 (± 12) | 56 (± 11) | 0.67 | 56 (± 11) | 54 (± 10) | 0.20 | 53 (± 12) | 54 (± 11) | 0.43 |
| ∆CPPopt > 10 mm Hg (%) | 16 (± 9) | 15 (± 9) | 0.42 | 21 (± 12) | 21 (± 13) | 0.66 | 25 (± 15) | 21 (± 12) | 0.08 |
| PRx (coefficient) | 0.13 (± 0.12) | 0.15 (± 0.13) | 0.18 | 0.14 (± 0.16) | 0.17 (± 0.15) | 0.18 | 0.15 (± 0.12) | 0.22 (± 0.16) | 0.001 |
| PRx > 0.05 (%) | 59 (± 15) | 61 (± 15) | 0.42 | 60 (± 19) | 62 (± 16) | 0.38 | 61 (± 14) | 67 (± 17) | 0.01 |
| Body temperature > 38C (%) | 15 (± 19) | 13 (± 16) | 0.44 | 55 (± 29) | 54 (± 27) | 0.93 | 51 (± 29) | 61 (± 28) | 0.01 |
p Values in bold and bold italics are considered statistically significant