Table 2.
Adjusted analysis of 1-year mortality
| Predictor (reference category) | Odds ratio (95% CI) | p value |
|---|---|---|
| Age | 1.03 (1.03–1.04) | < 0.001 |
| Admission diagnosis | ||
| TBI | 1 (reference) | |
| CA | 1.53 (1.32–1.78) | < 0.001 |
| SAH | 1.61 (1.35–1.92) | < 0.001 |
| ICH + AIS | 2.3 (1.98–2.68) | < 0.001 |
| Premorbid physical performance independent in self-care (yes) | 0.53 (0.45–0.64) | < 0.001 |
| PaO2-group | ||
| Normoxemia 8.2–18.3 kPa | 1 (reference) | |
| Hyperoxemia > 18.3 kPa | 1.16 (0.85–1.59) | 0.34 |
| Hypoxemia < 8.2 kPa | 1.24 (0.96–1.61) | 0.10 |
| MAP tertiles, lowest in 24 h | ||
| < 60 mmHg | 1 (reference) | |
| 60–68 mmHg | 0.73 (0.64–0.84) | < 0.001 |
| > 68 mmHg | 0.80 (0.69–0.92) | 0.002 |
| Interaction PaO2-group * MAP tertiles | ||
| Normoxemia * MAP < 60 mmHg | 1 (reference) | |
| Hyperoxemia * MAP 60–68 mmHg | 0.76 (0.49–1.16) | 0.20 |
| Hypoxemia * MAP 60–68 mmHg | 0.83 (0.57–1.22) | 0.35 |
| Hyperoxemia * MAP > 68 mmHg | 1.03 (0.67–1.57) | 0.90 |
| Hypoxemia * MAP > 68 mmHg | 1.33 (0.86–2.06) | 0.20 |
| Vasoactive, any (yes) | 1.08 (0.96–1.21) | 0.20 |
| Intracranial pressure monitored (yes) | 0.92 (0.79–1.06) | 0.25 |
| Modified SAPS II scorea | 1.08 (1.08–1.09) | < 0.001 |
Area under the receiver operating characteristic curve 0.80 (95% CI 0.79–0.81)
Hosmer–Lemeshow Ĉ goodness-of-fit p < 0.05
AIS acute ischemic stroke, CA cardiac arrest, CI confidence interval, ICH intracranial hemorrhage, modified SAPS II (Simplified Acute Physiology Score II excluding points for age, oxygenation, systolic blood pressure, and type of admission), SAH subarachnoid hemorrhage, TBI traumatic brain injury
aSAPS II score excluding point for age, admission type, oxygenation, and systolic blood pressure