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. 2021 May 17;12:2871. doi: 10.1038/s41467-021-23114-y

Table 2.

Percentages of pertussis seroprevalence and Dt and TT seroprotection per country and by age group.

IgG-PT (IU/mL) IgG-Dt (IU/mL) IgG-TT (IU/mL)
<LLOQ 50 to <100 ≥100 <0.01 <0.1 <0.01 <0.1
Country Age group N total % % N % a% corr. N % N % N % N % N
AT 40–49 250 11.2 28 5.2 4.3 13 10.4 26 53.6 134 0.0 0 1.6 4
50–59 250 5.2 13 3.6 2.2 9 20.0 50 59.2 148 0.0 0 1.6 4
Total 500 6.0 8.2 41 4.4 3.2 22 15.2 76 56.4 282 0.0 0 1.6 8
BE 40–49 252 7.1 18 7.5 7.4 19 13.5 34 54.8 138 0.0 0 6.0 15
50–59 252 11.5 29 7.1 6.8 18 27.8 70 63.1 159 1.2 3 8.7 22
Total 504 5.6 9.3 47 7.3 7.1 37 20.6 104 58.9 297 0.6 3 7.3 37
DK 40–49 249 7.6 19 5.6 4.9 14 12.9 32 52.6 131 0.4 1 4.0 10
50–59 242 9.5 23 11.2 12.1 27 15.3 37 52.9 128 0.0 0 5.8 14
Total 491 4.5 8.6 42 8.4 8.4 41 14.1 69 52.8 259 0.2 1 4.9 24
FI 40–49 250 4.0 10 2.0 0.1 5 3.2 8 20.4 51 0.0 0 0.4 1
50–59 250 6.8 17 1.6 b0.0 4 4.4 11 25.2 63 0.0 0 0.4 1
Total 500 6.6 5.4 27 1.8 b0.0 9 3.8 19 22.8 114 0.0 0 0.4 2
FR 40–49 299 9.4 28 4.4 3.2 13 2.0 6 23.1 69 0.0 0 2.7 8
50–59 298 10.4 31 8.1 8.0 24 10.7 32 48.0 143 0.0 0 3.4 10
Total 597 4.0 9.9 59 6.2 5.6 37 6.4 38 35.5 212 0.0 0 3.0 18
GR 40–49 250 6.0 15 4.8 3.8 12 26.8 67 72.4 181 0.0 0 11.6 29
50–59 250 5.2 13 3.2 1.7 8 59.6 149 91.6 229 4.8 12 31.2 78
Total 501 9.8 5.6 28 4.0 2.7 20 43.3 217 82.0 411 2.4 12 21.4 107
HU 40–49 260 5.0 13 1.5 b0.0 4 3.5 9 60.4 157 0.0 0 2.7 7
50–59 273 4.8 13 3.7 2.3 10 12.5 34 68.1 186 0.0 0 2.2 6
Total 533 4.5 4.9 26 2.6 0.9 14 8.1 43 64.4 343 0.0 0 2.4 13
IE 40–49 250 8.4 21 5.6 4.8 14 33.2 83 76.4 191 0.4 1 12.8 32
50–59 249 10.4 26 5.6 4.8 14 41.8 104 77.1 192 2.0 5 21.3 53
Total 499 3.8 9.4 47 5.6 4.8 28 37.5 187 76.8 383 1.2 6 17.0 85
LV 40–49 250 4.8 12 4.0 2.7 10 1.2 3 22.0 55 0.0 0 0.8 2
50–59 250 9.6 24 5.2 4.3 13 9.2 23 44.0 110 0.0 0 3.6 9
Total 500 5.2 7.2 36 4.6 3.5 23 5.2 26 33.0 165 0.0 0 2.2 11
LT 40–49 250 7.2 18 4.8 3.8 12 2.8 7 27.6 69 0.4 1 3.6 9
50–59 250 10.8 27 8.0 8.0 20 10.8 27 48.4 121 0.8 2 8.4 21
Total 500 2.8 9.0 45 6.4 5.8 32 6.8 34 38.0 190 0.6 3 6.0 30
NL 40–49 830 8.6 71 4.9 3.9 41 12.3 102 56.5 469 0.5 4 4.6 38
50–59 814 7.5 61 5.9 5.2 48 13.3 108 58.6 477 0.1 1 5.8 47
Total 1644 5.6 8.0 132 5.4 4.5 89 12.8 210 57.5 946 0.3 5 5.2 85
NO 40–49 251 12.0 30 7.6 7.4 19 5.6 14 31.9 80 0.0 0 3.6 9
50–59 251 13.1 33 11.2 12.1 28 8.8 22 32.7 82 0.4 1 6.8 17
Total 502 2.0 12.5 63 9.4 9.7 47 7.2 36 32.3 162 0.2 1 5.2 26
PT 40–49 250 6.0 15 4.0 2.7 10 7.6 19 42.4 106 0.0 0 0.4 1
50–59 250 6.4 16 4.4 3.2 11 10.0 25 41.6 104 0.0 0 0.4 1
Total 500 8.8 6.2 31 4.2 2.9 21 8.8 44 42.0 210 0.0 0 0.4 2
RO 40–49 252 7.1 18 4.0 2.7 10 25.8 65 77.4 195 0.0 0 4.0 10
50–59 252 11.1 28 4.0 2.7 10 25.0 63 74.2 187 0.4 1 12.3 31
Total 504 5.2 9.1 46 4.0 2.6 20 25.4 128 75.8 382 0.2 1 8.1 41
SK 40–49 250 6.0 15 7.2 6.9 18 5.2 13 64.4 161 0.0 0 2.0 5
50–59 250 5.6 14 4.8 3.8 12 6.8 17 71.2 178 0.4 1 1.2 3
Total 500 4.8 5.8 29 6.0 5.3 30 6.0 30 67.8 339 0.2 1 1.6 8
SI 40–49 263 7.2 19 4.6 3.5 12 1.9 5 26.6 70 0.0 0 0.4 1
50–59 261 5.0 13 3.8 2.5 10 10.3 27 37.9 99 0.0 0 1.5 4
Total 524 4.4 6.1 32 4.2 2.9 22 6.1 32 32.3 169 0.0 0 1.0 5
SE 40–49 253 9.5 24 6.3 5.8 16 11.5 29 58.5 148 0.0 0 5.5 14
50–59 251 6.0 15 4.0 2.7 10 21.1 53 62.2 156 0.4 1 6.4 16
Total 504 3.2 7.7 39 5.2 4.2 26 16.3 82 60.3 304 0.2 1 6.0 30
UK 40–49 250 4.0 10 5.2 4.3 13 24.8 62 71.6 179 1.2 3 7.6 19
50–59 249 5.6 14 4.4 3.3 11 35.7 89 79.1 197 0.4 1 8.8 22
Total 499 8.6 4.8 24 4.8 3.7 24 30.3 151 75.4 376 0.8 4 8.2 41

aIgG anti-PT percentage (%) ≥100 IU/mL corrected for assay sensitivity (Se = 78%) and specificity (Sp = 98%).

bCalculated negative IgG anti-PT percentage (%) ≥100 IU/mL changed to 0.0%.

Abbreviations of all participating countries are listed in Table 1.