Table 3.
GMCs for IgG-PT, IgG-Dt and IgG-TT in IU/mL per country and by age group.
| IgG-PT (IU/mL) | IgG-Dt (IU/mL) | IgG-TT (IU/mL) | |||||
|---|---|---|---|---|---|---|---|
| Country | Age group | GMC (95% CI) | p value | GMC (95% CI) | p value | GMC (95% CI) | p value |
| AT | 40–49 | 11.8 (9.8–14.1) | 0.08 (0.06–0.10) | 1.84 (1.64–2.07) | |||
| 50–59 | 7.8 (6.5–9.4) | 0.05 (0.04–0.06) | 1.85 (1.63–2.10) | ||||
| Total | 9.6 (8.4–10.9) | 0.002 | 0.06 (0.06–0.07) | 0.008 | 1.85 (1.70–2.01) | 0.952 | |
| BE | 40–49 | 12.1 (10.1–14.4) | 0.07 (0.06–0.09) | 1.64 (1.38–1.95) | |||
| 50–59 | 12.4 (10.4–14.9) | 0.04 (0.03–0.05) | 1.34 (1.09–1.64) | ||||
| Total | 12.2 (10.8–13.9) | 0.829 | 0.05 (0.05–0.06) | <0.001 | 1.48 (1.30–1.69) | 0.136 | |
| DK | 40–49 | 10.8 (9.0–13.0) | 0.08 (0.07–0.10) | 1.80 (1.52–2.13) | |||
| 50–59 | 13.3 (11.0–15.9) | 0.08 (0.06–0.09) | 2.02 (1.70–2.41) | ||||
| Total | 12.0 (10.5–13.6) | 0.128 | 0.08 (0.07–0.09) | 0.739 | 1.91 (1.69–2.15) | 0.346 | |
| FI | 40–49 | 7.4 (6.2–8.9) | 0.29 (0.24–0.36) | 3.23 (2.93–3.57) | |||
| 50–59 | 8.0 (6.7–9.6) | 0.22 (0.18–0.27) | 3.10 (2.77–3.47) | ||||
| Total | 7.7 (6.8–8.8) | 0.544 | 0.25 (0.22–0.29) | 0.053 | 3.16 (2.94–3.41) | 0.582 | |
| FR | 40–49 | 12.9 (10.9–15.2) | 0.27 (0.23–0.33) | 1.94 (1.72–2.20) | |||
| 50–59 | 14.0 (11.8–16.5) | 0.09 (0.08–0.11) | 1.28 (1.12–1.45) | ||||
| Total | 13.4 (11.9–15.1) | 0.502 | 0.16 (0.14–0.18) | <0.001 | 1.58 (1.44–1.73) | <0.001 | |
| GR | 40–49 | 8.0 (6.7–9.6) | 0.03 (0.02–0.04) | 0.62 (0.51–0.75) | |||
| 50–59 | 7.6 (6.3–9.1) | 0.01 (0.01–0.01) | 0.21 (0.17–0.26) | ||||
| Total | 7.8 (6.9–8.9) | 0.675 | 0.01 (0.01–0.02) | <0.001 | 0.36 (0.31–0.42) | <0.001 | |
| HU | 40–49 | 7.5 (6.3–8.9) | 0.08 (0.07–0.10) | 2.38 (2.02–2.79) | |||
| 50–59 | 8.2 (6.9–9.7) | 0.05 (0.04–0.07) | 2.24 (1.92–2.62) | ||||
| Total | 7.8 (6.9–8.8) | 0.495 | 0.07 (0.06–0.08) | 0.006 | 2.31 (2.06–2.58) | 0.614 | |
| IE | 40–49 | 10.7 (8.9–12.8) | 0.02 (0.02–0.03) | 0.79 (0.64–0.97) | |||
| 50–59 | 12.2 (10.1–14.6) | 0.02 (0.02–0.02) | 0.64 (0.50–0.81) | ||||
| Total | 11.4 (10.0–12.9) | 0.317 | 0.02 (0.02–0.02) | 0.006 | 0.71 (0.60–0.83) | 0.184 | |
| LV | 40–49 | 7.0 (5.8–8.4) | 0.26 (0.21–0.31) | 1.94 (1.70–2.20) | |||
| 50–59 | 11.1 (9.2–13.2) | 0.11 (0.09–0.14) | 1.42 (1.21–1.65) | ||||
| Total | 8.8 (7.7–10.0) | <0.001 | 0.17 (0.15–0.20) | <0.001 | 1.66 (1.50–1.83) | 0.002 | |
| LT | 40–49 | 10.6 (8.8–12.7) | 0.17 (0.14–0.21) | 1.29 (1.10–1.51) | |||
| 50–59 | 15.0 (12.5–18.0) | 0.08 (0.07–0.10) | 1.03 (0.85–1.24) | ||||
| Total | 12.6 (11.1–14.3) | 0.007 | 0.12 (0.10–0.13) | <0.001 | 1.15 (1.02–1.30) | 0.076 | |
| NL | 40–49 | 9.7 (8.7–10.7) | 0.06 (0.06–0.07) | 1.24 (1.13–1.36) | |||
| 50–59 | 11.2 (10.2–12.4) | 0.06 (0.06–0.07) | 1.20 (1.10–1.32) | ||||
| Total | 10.4 (9.7–11.2) | 0.037 | 0.06 (0.06–0.07) | 0.700 | 1.22 (1.14–1.30) | 0.690 | |
| NO | 40–49 | 13.0 (10.9–15.6) | 0.17 (0.14–0.21) | 1.45 (1.24–1.68) | |||
| 50–59 | 16.9 (14.1–20.2) | 0.16 (0.13–0.19) | 1.18 (0.98–1.41) | ||||
| Total | 14.8 (13.1–16.9) | 0.047 | 0.16 (0.14–0.19) | 0.553 | 1.31 (1.16–1.47) | 0.084 | |
| PT | 40–49 | 6.9 (5.7–8.2) | 0.12 (0.10–0.15) | 2.63 (2.36–2.92) | |||
| 50–59 | 8.8 (7.4–10.6) | 0.11 (0.09–0.14) | 2.63 (2.38–2.91) | ||||
| Total | 7.8 (6.8–8.8) | 0.055 | 0.12 (0.10–0.14) | 0.688 | 2.63 (2.44–2.83) | 0.974 | |
| RO | 40–49 | 9.9 (8.3–11.9) | 0.03 (0.02–0.04) | 0.80 (0.69–0.93) | |||
| 50–59 | 10.9 (9.1–13.0) | 0.03 (0.02–0.04) | 0.56 (0.47–0.66) | ||||
| Total | 10.4 (9.1–11.8) | 0.479 | 0.03 (0.03–0.03) | 0.762 | 0.67 (0.60–0.75) | 0.002 | |
| SK | 40–49 | 9.5 (7.9–11.4) | 0.06 (0.05–0.08) | 1.56 (1.36–1.80) | |||
| 50–59 | 8.2 (6.8–9.8) | 0.05 (0.04–0.06) | 1.64 (1.42–1.89) | ||||
| Total | 8.8 (7.8–10.0) | 0.254 | 0.06 (0.05–0.07) | 0.168 | 1.60 (1.45–1.77) | 0.632 | |
| SI | 40–49 | 10.4 (8.7–12.4) | 0.18 (0.14–0.22) | 2.03 (1.79–2.30) | |||
| 50–59 | 8.6 (7.2–10.3) | 0.12 (0.09–0.14) | 2.01 (1.76–2.30) | ||||
| Total | 9.4 (8.3–10.7) | 0.150 | 0.14 (0.12–0.17) | 0.004 | 2.02 (1.85–2.21) | 0.916 | |
| SE | 40–49 | 11.6 (9.7–13.9) | 0.07 (0.06–0.09) | 1.14 (0.97–1.36) | |||
| 50–59 | 9.4 (7.8–11.2) | 0.05 (0.04–0.06) | 1.22 (1.01–1.46) | ||||
| Total | 10.4 (9.2–11.8) | 0.100 | 0.06 (0.05–0.07) | 0.012 | 1.18 (1.04–1.34) | 0.626 | |
| UK | 40–49 | 7.3 (6.1–8.8) | 0.03 (0.03–0.04) | 0.86 (0.72–1.02) | |||
| 50–59 | 7.2 (6.0–8.6) | 0.02 (0.02–0.03) | 0.80 (0.67–0.95) | ||||
| Total | 7.2 (6.4–8.2) | 0.901 | 0.03 (0.02–0.03) | 0.001 | 0.83 (0.73–0.93) | 0.578 | |
P values are given for the difference between the two age groups. Abbreviations of all participating countries and the number of samples included in the study are listed in Table 1.