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. 2021 May 17;11:10459. doi: 10.1038/s41598-021-90065-1

Table 3.

MRI parameters before and after RT.

Baseline MRI First post-RT MRI P value
ADC (× 10–3 mm2/s) 0.67 (0.61–0.72) 0.75 (0.63–1.43) 0.027
Ktrans (× 10–3/min) 135.38 (43.51–346.04) 100.08 (38.62–257.49) 0.106
kep (× 10–3/min) 836.33 (301.41–1082.32) 335.80 (21.86–741.87) 0.002
ve (× 10–3) 161.54 (128.38–410.13) 273.99 (181.39–1216.95) 0.027
vp (× 10–3) 4.93 (0.38–24.52) 2.86 (0.21–33.35) 0.625
Volume (cm3) 9.90 (0.80–65.93) 10.40 (1.01–60.93) 0.770

Numbers are medians and ranges in parentheses.

MRI, magnetic resonance imaging; ADC, apparent diffusion coefficient; Ktrans, volume transfer constant; kep, rate constant; RT, radiation therapy; ve, volume fraction of the extravascular extracellular matrix; vp, blood plasma volume.