TABLE 2:
Predictors of Complete Remission of Dysplasia in Barrett’s esophagus patients undergoing endoscopic therapy
| Univariate HR (95% CI) | P-Value | Multivariate HR (95% CI) | P-Value | |
|---|---|---|---|---|
| Age | ||||
| 10-Year Increments | 1.04 (0.95–1.15) | 0.36 | 1.03 (0.93–1.40) | 0.55 |
| Sex | ||||
| Female | REF | REF | ||
| Male | 1.12 (0.88–1.44) | 0.35 | 1.25 (0.97–1.61) | 0.09 |
| BMI | ||||
| ≥30 | REF | REF | ||
| <30 | 0.94 (0.78–1.12) | 0.47 | 1.19 (0.99–1.44) | 0.07 |
| Smoking | ||||
| Never | REF | REF | ||
| Ever | 1.20 (0.99–1.46) | 0.06 | 1.15 (0.93–1.41) | 0.20 |
| Barrett’s Length | ||||
| 1 cm Increments | 0.91 (0.89–0.94) | <.01 | 0.90 (0.88–0.93) | <.01 |
| Hiatal Hernia | ||||
| Absent | REF | REF | ||
| Present | 0.90 (0.71–1.16) | 0.42 | 0.96 (0.74–1.25) | 0.76 |
| Treatment Group | ||||
| ESD | REF | REF | ||
| Cap EMR | 0.41 (0.31–0.54) | <.01 | 0.42 (0.29–0.59) | <.01 |
| Worst Histology | ||||
| HGD/EAC | REF | REF | ||
| LGD | 1.02 (0.82–1.27) | 0.89 | 0.99 (0.78–1.25) | 0.93 |
OR: Odds Ratio; REF: Reference; BMI: Body Mass Index; ESD: Endoscopic Submucosal Dissection; EMR: Endoscopic Mucosal Resection; LGD: Low Grade Dysplasia; HGD: High Grade Dysplasia; EAC: Esophageal Adenocarcinoma