TABLE 3:
Predictors of Complete Remission of Intestinal Metaplasia in Barrett’s esophagus patients undergoing endoscopic therapy
| Univariate HR (95% CI) | P-Value | Multivariate HR (95% CI) | P-Value | |
|---|---|---|---|---|
| Age | ||||
| 10-Year Increments | 0.93 (0.84–1.03) | 0.15 | 0.96 (0.86–1.06) | 0.40 |
| Sex | ||||
| Female | REF | REF | ||
| Male | 1.01 (0.78–1.32) | 0.93 | 1.14 (0.86–1.50) | 0.36 |
| BMI | ||||
| ≥30 | REF | REF | ||
| <30 | 0.93 (0.77–1.14) | 0.51 | 1.26 (1.03–1.55) | 0.03 |
| Smoking | ||||
| Never | REF | REF | ||
| Ever | 1.12 (0.91–1.39) | 0.28 | 1.02 (0.82–1.28) | 0.84 |
| Barrett’s Length | ||||
| 1 cm Increments | 0.86 (0.83–0.89) | <.01 | 0.86 (0.83–0.89) | <.01 |
| Hiatal Hernia | ||||
| Absent | REF | REF | ||
| Present | 0.78 (0.60–1.02) | 0.07 | 0.83 (0.63–1.10) | 0.19 |
| Treatment Group | ||||
| ESD | REF | REF | ||
| Cap EMR | 0.74 (0.52–1.07) | 0.11 | 0.78 (0.48–1.27) | 0.32 |
| Worst Histology | ||||
| HGD/EAC | REF | REF | ||
| LGD | 0.9 (0.71–1.16) | 0.42 | 1.10 (0.85–1.42) | 0.47 |
OR: Odds Ratio; REF: Reference; BMI: Body Mass Index; ESD: Endoscopic Submucosal Dissection; EMR: Endoscopic Mucosal Resection; LGD: Low Grade Dysplasia; HGD: High Grade Dysplasia; EAC: Esophageal Adenocarcinoma