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. 2021 May 4;8:627022. doi: 10.3389/fmolb.2021.627022

FIGURE 1.

FIGURE 1

CASC9 overexpression is correlated with poor survival in CRC. (A) Boxplot CASC9 expressions of CRC tissues (n = 275) compared with normal samples (n = 349) from TCGA-COAD dataset (http://gepia.cancer-pku.cn/detail.php) showing that CASC9 was significantly upregulated in CRC tissues with a Log2FC cutoff value 2.0 and P < 0.01 (*). (B) The expression profiles, number of TPM, and HR (%) were used to plot overall survival. Higher expression of CASC9 in CRC tissue is associated with poor overall survival. (C) CASC9 expression was extracted from ENCORI-COAD dataset (Li et al., 2013). Four hundred seventeen tumor samples and 41 normal tissues were used from the dataset. Boxplot analysis showed that CASC9 was upregulated in tumor tissues. (D) The log-rank P < 0.05, HR, and high/low expression numbers were used to plot survival curve from ENCORI-Pan-Cancer. Higher expression of CASC9 reduced the overall survival of patients. TCGA, The Cancer Genome Atlas; COAD, colon adenocarcinoma; ENCORI, The Encyclopedia of RNA Interactomes; TPM, transcript per million, HR, hazard ratio.