eFigure.

Study design: The EPRA (Effectiveness of Pulmonary Rehabilitation for Patients with Asthma) study combines a randomized control group study with a waiting-list group design (T0 to T3; T0, study inclusion/ randomization; T1, start of rehabilitation for intervention group [IG]; T2, end of rehabilitation for IG;

T3, 3 months after the end of rehabilitation for IG, or start of rehabilitation for the control group [CG]), with a subsequent pooled observational study (follow-up of both study groups for up to 12 months after end of rehabilitation).