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. 2021 May 17;11:10438. doi: 10.1038/s41598-021-89973-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Deletion analysis of the human TARDBP promoter. Firefly luciferase activity of TARDBP promoter deletants in different cell lines (HEK293, HeLa, SH-SY5Y and Neuro2A) was measured in the cell lysate and values were normalized against Renilla. Activity of deletants is expressed as-fold against the cells transfected with the 1316 construct (= 1). Bars indicate the mean value of three independent assays. Error bars indicate standard deviation: *p < 0.05, and **p < 0.01 (One way ANOVA with Tukey test).