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. 2021 May 17;11:10439. doi: 10.1038/s41598-021-89836-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The induction of radiation induced genes, MafB and IL4, in the thymus. (a) The schematic illustration indicates the method to examine expression of radiation induced genes. Sublethal total body irradiation (SL-TBI) was performed. Thymic RNA was extracted and q-PCR was performed. (b) Prominent MafB gene induction after SL-TBI was detected at Day1 in WT. (c) The expression of IL4 after the SL-TBI. Prominent induction of IL4 was detected after 1 day SL-TBI. (d) The less prominent induction of MafB expression was reduced in the MafB^+/GFP mutant mice. (e) The less prominent of IL4 induction after irradiation in the MafB^+/GFP mutant mice. *P < 0.05, **P < 0.01 (Tukey Kramer method).