Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 17;12:2889. doi: 10.1038/s41467-021-23151-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Cryo-EM reconstruction obtained for the 16-mer complex formed by 8 ANTH and 8 ENTH units (A₈E₈). The density corresponding to ANTH and ENTH is colored correspondingly in cyan and gray. b Model of the A₈E₈ complex built based on the EM density shown in cartoon representation. One tetramer is colored with the ANTH domains in cyan and ENTH domains in gray (see Supplementary Fig. 4 for symmetry axes). c The building unit is the AENTH tetramer (A₂E₂) shown in cartoon and surface representation, with the ENTH domains in gray and the ANTH domains in cyan. The PIP₂ polar heads bound to the tetramer are shown in stick representation (gold). A schematic of the tetramer is shown next to the structure.