Table 2.
Results of network meta-analysis for all possible treatment effects.
| EA | − 3.78 (− 6.26, − 1.33) | − 1.14 (− 3.63, 1.32) | − 2.14 (− 4.37, 0.04) | − 1.11 (− 7.57, 5.27) | 3.26 (− 3.32, 9.84) | 1.43 (− 4.94, 7.8) | 12.87 (5.56, 20.15) | 0.33 (− 1.49, 2.12) |
| 3.78 (1.33, 6.26) | EA with SSRIs | 2.64 (0.1, 5.19) | 1.63 (− 0.52, 3.79) | 2.66 (− 3.81, 9.1) | 7.04 (0.03, 14.1) | 5.2 (− 1.63, 12.06) | 16.65 (9.34, 23.98) | 4.11 (2.33, 5.89) |
| 1.14 (− 1.32, 3.63) | − 2.64 (− 5.19, − 0.1) | MA | − 1.01 (− 3.24, 1.22) | 0.03 (− 5.9, 5.93) | 4.4 (− 2.63, 11.45) | 2.56 (− 4.27, 9.45) | 14.02 (7.15, 20.89) | 1.47 (− 0.37, 3.3) |
| 2.14 (− 0.04, 4.37) | − 1.63 (− 3.79, 0.52) | 1.01 (− 1.22, 3.24) | MA with SSRIs | 1.03 (− 5.3, 7.36) | 5.41 (− 1.52, 12.37) | 3.57 (− 3.15, 10.36) | 15.02 (7.8, 22.25) | 2.47 (1.11, 3.85) |
| 1.11 (− 5.27, 7.57) | − 2.66 (− 9.1, 3.81) | − 0.03 (− 5.93, 5.9) | − 1.03 (− 7.36, 5.3) | NASSAs | 4.38 (− 4.79, 13.59) | 2.54 (− 6.49, 11.63) | 14 (4.91, 23.07) | 1.44 (− 4.74, 7.64) |
| − 3.26 (− 9.84, 3.32) | − 7.04 (− 14.1, − 0.03) | − 4.4 (− 11.45, 2.63) | − 5.41 (− 12.37, 1.52) | − 4.38 (− 13.59, 4.79) | Sham EA | − 1.83 (− 8.51, 4.83) | 9.62 (− 0.26, 19.46) | − 2.94 (− 9.78, 3.9) |
| − 1.43 (− 7.8, 4.94) | − 5.2 (− 12.06, 1.63) | − 2.56 (− 9.45, 4.27) | − 3.57 (− 10.36, 3.15) | − 2.54 (− 11.63, 6.49) | 1.83 (− 4.83, 8.51) | Sham EA with SSRIs | 11.46 (1.74, 21.12) | − 1.09 (− 7.75, 5.53) |
| − 12.87 (− 20.15, − 5.56) | − 16.65 (− 23.98, − 9.34) | − 14.02 (− 20.89, − 7.15) | − 15.02 (− 22.25, − 7.8) | − 14 (− 23.07, − 4.91) | − 9.62 (− 19.46, 0.26) | − 11.46 (− 21.12, − 1.74) | Sham MA | − 12.54 (− 19.64, − 5.44) |
| − 0.33 (− 2.12, 1.49) | − 4.11 (− 5.89, − 2.33) | − 1.47 (− 3.3, 0.37) | − 2.47 (− 3.85, − 1.11) | − 1.44 (− 7.64, 4.74) | 2.94 (− 3.9, 9.78) | 1.09 (− 5.53, 7.75) | 12.54 (5.44, 19.64) | SSRIs |
The estimates of mean difference of treatments in the columns versus rows presented in the lower diagonal elements (while those of the row treatments vs. column treatments are presented in the upper diagonal elements). Significant results are in bold and underscored.
EA electroacupuncture, MA manual acupuncture, SSRIs selective serotonin reuptake inhibitors, NASSAs noradrenaline and specific serotoninergic antidepressants, TCAs tricyclic antidepressants.