Table 3.
Clinicopathological features in cBCCs and TERTp mutation status.
| Clinicopathological features | Total cBCCs (n = 142) | TERTwt (n = 80) | TERTmut (n = 62) | p value |
|---|---|---|---|---|
| Age at diagnosis (mean ± SD) (n = 142) | 72.4 ± 11.2 | 72.4 ± 11.1 | 72.7 ± 11.3 | 0.887 |
| Sex [n (%)] (n = 142) | ||||
| Male | 78 (54.9) | 46 (57.5) | 32 (51.6) | 0.484 |
| Female | 64 (45.1) | 34 (42.5) | 30 (48.4) | |
| Skin melanin content (inner arm) (mean ± SD) (n = 114) | 28.3 ± 3.3 | 28.3 ± 3.7 | 28.2 ± 2.8 | 0.924 |
| Sun exposure (mean ± SD) (n = 121) | ||||
| Low | 30 (24.8) | 17 (25.4) | 13 (24.1) | 0.869 |
| High | 91 (75.2) | 50 (74.6) | 41 (75.9) | |
| Location [n (%)] (n = 142) | ||||
| Nose | 31 (21.8) | 17 (21.3) | 14 (22.6) | 0.876 |
| Face | 43 (30.3) | 23 (28.7) | 20 (32.3) | |
| Eyelid | 30 (21.1) | 21 (26.3) | 9 (14.5) | |
| Preauricular/Auricular region | 26 (18.3) | 14 (17.5) | 12 (19.4) | |
| Scalp | 1 (0.7) | 0 (0) | 1 (1.6) | |
| Lip | 5 (3.5) | 3 (3.8) | 2 (3.2) | |
| Other | 6 (4.2) | 2 (2.5) | 4 (6.5) | |
| Tumor dimension (mean ± SD) (n = 142) | 13.6 ± 10.1 | 14.0 ± 11.7 | 13.1 ± 7.7 | 0.612 |
| Other | ||||
| Focality [n (%)] (n = 142) | ||||
| Single | 56 (39.4) | 35 (43.8) | 21 (33.9) | 0.232 |
| Multiple | 86 (60.6) | 45 (56.2) | 41 (66.1) | |