Table 5.
Features significantly associated with TERTp mutation status in indolent-type growth pattern cBCCs.
| Features | Total (n = 51) | wt (n = 32) | TERTp (n = 19) | p value |
|---|---|---|---|---|
| Sex [n (%)] | ||||
| Male | 23 (45.1) | 18 (56.3) | 5 (26.3) | 0.038 |
| Female | 28 (54.9) | 14 (43.7) | 14 (73.7) | |
| Focality [n (%)] | ||||
| Single | 20 (39.2) | 16 (50.0) | 4 (21.1) | 0.041 |
| Multiple | 31 (60.8) | 16 (50.0) | 15 (78.9) | |
| p53 | ||||
| p53 negative (< 10%) | 16 (38.0) | 3 (15.8) | 13 (46.4) | 0.020 |
| p53 positive (≥ 10%) | 31 (62.0) | 16 (84.2) | 15 (53.6) | |
| Necrosis | ||||
| Absent | 38 (74.5) | 29 (90.6) | 10 (52.6) | 0.005 |
| Present | 23 (23.5) | 3 (9.4) | 9 (47.4) | |
Bold - significant difference (p-value < 0.05).