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. 2021 Apr 15;13(4):2350–2364.

Figure 1.

Figure 1

Up-regulating miR-378 alleviates hemodynamics and myocardial injury in MI/RI mice. (A, B) The value of LVSP and LVEDP in MI/RI mice after up-regulating miR-378; (C) The value of ± dp/dtmax in MI/RI mice after up-regulating miR-378; (D-G) The activities of AST, CK, CK-MB and LDH in MI/RI mice after up-regulating miR-378; (H-L) The levels of SOD, MDA, GSH-Px, CAT and NO in MI/RI mice after up-regulating miR-378; (M) HE staining results in MI/RI mice after up-regulating miR-378 (× 200; Scale bar = 50 μm); * vs the sham group, P < 0.05; # vs the I/R group, P < 0.05; + vs the anti-miR-378 group, P < 0.05; 6 mice in each group (A-C) and 5 mice in each group (D-M). The data were expressed in the form of mean ± standard deviation. One-way ANOVA was used for data analysis, and Tukey’s post hoc test was used for pairwise comparison after ANOVA analysis.