Table 1.
Baseline data
| Baseline data | DMED group (n=84) | Control (n=84) | t/χ2 | P |
|---|---|---|---|---|
| Gender (n, %) | 0.095 | 0.758 | ||
| Male | 42 (50.00) | 40 (47.62) | ||
| Female | 42 (50.00) | 44 (52.38) | ||
| Age (month) | 33.2±18.4 | 32.3±15.3 | 0.391 | 0.696 |
| BMI (kg/m2) | 11.6±3.1 | 11.9±2.9 | 0.648 | 0.518 |
| Height (cm) | 86.28±15.34 | 89.11±18.04 | 1.173 | 0.242 |
| BSA (m2) | 0.60±0.15 | 0.57±0.17 | 1.213 | 0.227 |
| ASD (number, %) | 22 (26.19) | 20 (23.81) | 0.525 | 0.469 |
| VSD (number, %) | 62 (73.81) | 64 (76.19) | ||
| Anesthesia duration (min) | 237.89±51.64 | 248.55±56.23 | 1.331 | 0.185 |
| Operation duration (min) | 186.65±45.21 | 192.62±46.44 | 0.855 | 0.394 |
| CPB duration (min) | 105.83±35.65 | 108.21±38.36 | 0.532 | 0.595 |
| Aorta blocking period (min) | 68.38±28.95 | 66.32±35.72 | 0.409 | 0.683 |
| Cooling threshold (°C) | 32.61±1.28 | 32.35±1.47 | 1.491 | 0.138 |
| Vasoactive drugs used in the surgery (n, %) | ||||
| Epinephrine | 1 (1.19) | 2 (2.38) | 0.339 | 0.560 |
| Dopamine | 2 (2.38) | 4 (4.76) | 0.173 | 0.678 |
| Milrinone | 6 (7.14) | 5 (5.95) | 0.097 | 0.755 |
| Intraoperative fluid volume (mL) | 172.54±52.57 | 169.61±49.85 | 0.367 | 0.714 |
| Urine output | ||||
| During CPB (mL/kg.h) | 2.23±1.18 | 2.41±1.19 | 1.289 | 0.199 |
| After CPB (mL/kg.h) | 2.56±1.92 | 2.24±2.13 | 0.971 | 0.333 |
| T2 (mL/kg.h) | 2.94±1.04 | 2.56±2.32 | 0.365 | 0.715 |
| T3 (mL/kg.h) | 3.72±1.36 | 3.35±1.47 | 1.440 | 0.152 |
| T4 (mL/kg.h) | 3.85±1.27 | 3.63±1.56 | 0.365 | 0.615 |
Notes: T2: 24 h after operation; T3: 48 h after operation; T4: 72 h after operation; BSA: body surface area; CPB: cardiopulmonary bypass; ASD: atrial septal defect; VSD: ventricular septal defect; DMED: dexmedetomidine; BMI body mass index.