Table 3.
Biological processes or signaling pathways associated with SIX1 expression
| Gene set | ES | NES | NOM P-value | FDR q-value |
|---|---|---|---|---|
| PI3k/AKT/MTOR signaling | -0.50862 | -1.85568 | 0.004 | 0.044654 |
| Mitotic spindle | -0.60529 | -2.06665 | 0.004024 | 0.022918 |
| G2M checkpoint | -0.72909 | -2.05715 | 0.008032 | 0.01855 |
| E2F targets | -0.75283 | -1.96647 | 0.014 | 0.03592 |
| NOTCH signaling | -0.55541 | -1.8054 | 0.01417 | 0.055925 |
| Glycolysis | -0.45734 | -1.68532 | 0.024242 | 0.064034 |
| Cholesterol homeostasis | -0.48201 | -1.63903 | 0.027944 | 0.073193 |
| DNA repair | -0.53234 | -1.72811 | 0.041257 | 0.082555 |
| Estrogen response early | -0.41188765 | -1.5964891 | 0.04499 | 0.080924 |
SIX1, Sine oculis homeobox 1; ES, enrichment score; NES, normalized enrichment score; NOM P-val, nominal P value; FDR q-val, false discovery rate q value.