Table 2.
Clinical and Functional Outcomes of Osteochondral Defect Patients Treated With BMAC and CDM
| Demographics of the Patients, N = 14 | N (%) | P Value |
|---|---|---|
| Physical examination findings | ||
| Preoperative flexion,° | 123.9 (3.6) | |
| Postoperative flexion,° | 131.5 (6.3) | .002 |
| Effect size | 1.06 | |
| Hamstring∗ | ||
| Preoperative strength | ||
| 4– | 3 (33.3) | |
| 4 | 5 (55.6) | |
| 5 | 1 (11.1) | |
| Postoperative strength | ||
| 4 | 5 (45.5) | |
| 5 | 6 (54.5) | |
| Preoperative strength | 4.1 (0.35) | |
| Postoperative strength | 4.6 (0.52) | .33 |
| Effect size | 0.94 | |
| Quadriceps∗ | ||
| Preoperative strength | ||
| 3+ | 2 (15.4) | |
| 4– | 5 (38.5) | |
| 4 | 5 (38.5) | |
| 5 | 1 (7.7) | |
| Postoperative strength | ||
| 4 | 7 (53.8) | |
| 5 | 6(46.2) | |
| Preoperative strength | 4.0 (0.43) | |
| Postoperative strength | 4.5 (0.52) | .007 |
| Effect size | 0.96 | |
| Pain scores | ||
| Preoperative VAS | 4.5 (2.4) | |
| Postoperative VAS | 1.4 (1.6) | .001 |
| Effect size | 1.32 | |
| Functional outcomes | ||
| Preoperative UCLA | 5.7 (2.4) | |
| Postoperative UCLA | 6.6 (2.5) | .455 |
| Effect size | 0.23 | |
| Preoperative KOS-ADL | 53.8 (14.3) | |
| Postoperative KOS-ADL | 92.9 (12.4) | .007 |
| Effect size | 6.76 | |
| Preoperative KOS-Sports | 28.2 (15.7) | .560 |
| Postoperative KOS-Sports | 79.5 (20.3) | |
| Effect size | 1.51 |
NOTE. Values are given as the mean and standard deviation in parentheses.
ADL, activities of daily living; BMAC, bone marrow aspirate concentrate; CDM, cartilage-derived matrix; KOS, Knee Outcome Survey; UCLA: University of California, Los Angeles Activity Score; VAS, visual analog scale.
∗
Strength is based on a grading scale of 0-5.