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. 2021 May 4;9:660424. doi: 10.3389/fchem.2021.660424

SCHEME 3.

SCHEME 3

Synthesis of 4-((5,6-R-1H-benzo [d][1,2,3]triazol-1-yl)methyl)aniline (16–18). 1) Cs2CO3, DMF, 60°C for 48 h; 2) NH2NH2 (1:20), Pd/C (10% w/w), EtOH, 80°C for 2 h (to afford compounds 16 and 17); 3) CH3NHNH2 (1:10), EtOH, 100°C for 48 h in autoclave (to afford compound 18).