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. 2021 May 4;12:658420. doi: 10.3389/fimmu.2021.658420

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Copyright © 2021 Zhao, Schank, Wang, Li, Nguyen, Dang, Cao, Khanal, Nguyen, Thakuri, Ogbu, Lu, Wu, Morrison, Gazzar, Liu, Zhang, Ning, Moorman and Yao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CD4 T cell homeostasis in ART-controlled PLHIV and HS. (A, B) Flow cytometry analysis of frequencies (%) of CD4⁺ T cell subsets within PBMCs or CD71⁺ T cells within CD4⁺ T cells isolated from ART-controlled PLHIV and HS. (C) Percentages of CD4⁺ T cells within PBMCs isolated from HIV-INRs, HIV-IRs, and HS. (D) Percentages of CD4⁺CD45RA^- and CD4⁺CD45RA⁺ cell subsets within PBMCs from HIV-INRs, HIV-IRs, and HS. (E, F) Flow cytometry analysis of CD71 expression in CD4⁺, CD4⁺CD45RA⁺, and CD4⁺CD45RA^- cell subsets from HIV-INRs, HIV-IRs, and HS. (G, H) Flow cytometry analysis of CD71 expression in CD4⁺, CD4⁺CD45RA⁺ and CD4⁺CD45RA^- cell subsets within PBMCs from HIV-INRs, HIV-IRs, and HS following in vitro TCR stimulation for 5 days.