Figure 5.
mtTFA expression in CD4 T cells in ART-controlled PLHIV and HS. (A–D) Flow cytometry analysis of mtTFA expression in total CD4+, CD4+CD45RA+, CD4+CD45RA-, CD4+CD71+, CD4+CD71-, CD4+CD71+CD45RA+, CD4+CD71+CD45RA-, CD4+CD71-CD45RA+, and CD4+CD71-CD45RA+ cell subsets from HIV-INRs, HIV-IRs, and HS. (E) Spearman’s correlation between the frequency of mtTFA+ cells in the CD71+CD4+ subset and the percentage of CD4+ T cells within PBMCs from HIV-INRs, HIV-IRs, and HS. (F) Spearman’s correlation between the frequency of mtTFA+ cells in the CD71+ CD4+ subset and the percentage of CD71+ cells in HIV-INRs, HIV-IRs, and HS.