Table 2.
Comparison of hemodynamic parameters at baseline and after the norepinephrine injection.
| Hemodynamic variables | Baseline | Post-injection | p |
|---|---|---|---|
| HR (bpm) | 75.5 [63.0;91.2] | 79.0 [64.2;91.8] | 0.491 |
| SAP (mmHg) | 89 [84; 94] | 122 [114;130] | 0.001 |
| DAP (mmHg) | 46.5 [41.0;50.2] | 62.5 [55.5;67.2] | 0.001 |
| MAP (mmHg) | 60.5 [56.0;66.0] | 83.0 [76.5;89.0] | 0.001 |
| PP (mmHg) | 41.5 [35.0;46.5] | 57.5 [49.8;68.2] | <0.001 |
| CVP (mmHg) | 7.00 [5.50;9.00] | 8.50 [5.75;9.25] | <0.001 |
| SVV (%) | 17.2 [15.0;23.7] | 25.0 [21.9;33.3] | 0.002 |
| PPV (%) | 14.5 [10.5;18.2] | 9.50 [7.00;14.5] | 0.027 |
| Eadyn | 0.93 [0.47;1.27] | 0.40 [0.30;0.60] | 0.042 |
| MSP (mmHg) | 23.0 [18.5;26.0] | 19.0 [14.8;24.0] | 0.149 |
| VRi (mmHg ml−1·m−2) | 2.79 [2.63;2.98] | 3.06 [2.76;3.26] | 0.005 |
| CCP (mmHg) | 26.1 [19.4;29.1] | 54.8 [39.8;70.3] | 0.001 |
| SARi (mmHg ml−1·m−2) | 18.4 [14.5;25.8] | 11.4 [6.06;18.5] | 0.002 |
| CCP-MSP (mmHg) | 5.74 [−3.8;11.1] | 42.0 [17.1;48.0] | 0.001 |
| SVi (ml·m−2) | 23.0 [17.5;28.8] | 28.0 [19.0;36.0] | 0.034 |
| CI (ml min−1·m−2) | 1.66 [1.56;2.09] | 1.96 [1.82;2.32] | 0.010 |
| EA (mmHg ml−1·m−2) | 1.66 [1.41;2.31] | 1.75 [1.50;3.25] | 0.003 |
| Total CA (ml mmHg−1·m−2) | 1.27 [1.01;1.61] | 0.95 [0.78;1.22] | 0.016 |
| TPRi (mmHg ml−1·m−2) | 29.0 [24.5;39.0] | 36.0 [29.2;43.0] | 0.004 |
| Ventricular elastance (EV; mmHg ml−1·m−2) | 1.2 [0.9;1.9] | 1.74 [1.1;2.4] | 0.002 |
| EA/EV ratio (units) | 1.4 [1.1;1.9] | 1.3 [1;1.9] | 0.215 |
Values are expressed as the mean ± SD or the median [IQR]. CA, arterial compliance; CI, cardiac index; CVP, central venous pressure; DAP, diastolic arterial pressure; EA, arterial elastance; Eadyn, dynamic arterial elastance; EV, ventricular elastance; PPV, pulse pressure variation; HR, heart rate; MAP, mean arterial pressure; CCP, critical closing pressure; PP, pulse pressure; TPRi, indexed total peripheral resistance; SAP, systolic arterial pressure; SARi, indexed systemic arterial resistance; SVi, indexed stroke volume; SVV, stroke volume variation; VRi, indexed systemic venous resistance. The value of p refers to the within-group (before/after) comparison. Bold values are values with p < 0.05.