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. 2021 May 4;12:606682. doi: 10.3389/fphar.2021.606682

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Copyright © 2021 Li, Ren, Wang, Ma, Chen, Xie, Li, Li and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mechanism of borneol against cerebral ischemia injury and chemical structure of three borneols. (A) Levorotatory borneol (endo-(1 S)-1,7,7-trimethyl-bicyclo [2.2.1] heptan-2-ol, (–)-borneol), which is extracted from fresh leaves of Blumea balsamifera (L.) DC. (B) Dextrorotatory borneol (endo-(1R)-1,7,7-trimethyl-bicyclo [2.2.1] heptan-2-ol, (+)-borneol), which is extracted from fresh branches and leaves of Cinnamomum camphora (L.) Presl. (C) Synthetic borneol (DL-borneol) is an optically inactive (±) borneol that is mainly a mixture of (±) borneol and is obtained via the chemical transformation of camphor and turpentine oil.