TABLE 2.

Quality assessment of included studies.

Study years	A	B	C	D	E	F	G	Total
Li (2018)	+	+	+		+	+	+	6
Wang et al. (2018)	+	+			+		+	4
Yu et al. (2020)	+	+			+	+	+	5
Yu et al. (2016)	+	+			+	+	+	5
Yu et al. (2019a)	+	+			+		+	4
He (2005)	+	+			+		+	4
He et al. (2006)	+	+			+	+	+	5
He et al. (2007)	+	+			+	+	+	5
Huang (2018)	+	+			+	+	+	5
Tian (2013)	+	+			+	+	+	5
Ni (2011)	+	+			+	+	+	5
Tang (2010)	+	+			+	+	+	5
Wen (2017)	+	+			+	+	+	5
Dong et al. (2018)	+	+			+	+	+	5
Wu et al. (2014)	+	+	+		+	+	+	6
Xu et al. (2016)	+	+			+		+	4
Jia (2014)	+	+			+	+	+	5
Chang et al. (2017)	+	+	+		+	+	+	6
Shao et al. (2018)	+	+			+		+	4
Yan et al. (2018)	+	+			+		+	4
Huang et al. (2001)	+	+					+	3
Wang (2011)	+	+			+	+	+	5
Duan et al. (2012)	+	+			+		+	4
Liu et al. (2018)	+	+					+	3
Liu et al. (2007)	+	+			+		+	4
Yao et al. (2011)	+	+			+		+	4

A, peer-reviewed publication; B, random allocation; C, blinded conduct of the Experiments; D, blinded assessment of outcome; E, use of anesthetic without significant neuroprotection; F, compliance with animal welfare regulations; G, detailed description of animals and models.