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. 2021 May 4;12:666732. doi: 10.3389/fphar.2021.666732

TABLE 7.

List of selected plant material with documented impact on NET formation.

Plant family Species Plant extract/s or compound/s Cellular target and mechanism of action Effect on NET formation References
1 Anacardiaceae Anacardium occidentale L Plant extract Activation of PI3 kinase and surface-expressed G protein-coupled sphingosine-1-phosphate (S1P) receptors Increased NET formation Hollands et al. (2016)
2 Asteraceae Verbesina erstediana benth Plant extract n.d Increased NET formation Yaseen et al. (2017)
3 Lamiaceae Salvia miltiorrhiza bunge Plant extract Inhibition of myeloperoxidase (MPO) and NADPH oxidase (NOX) activity Decreased NET formation Tao et al. (2018)
4 Meliaceae Guarea kunthiana A.Juss Plant extract n.d Increased NET formation Jerjomiceva et al. (2016)
5 Myrtaceae Eugenia aurata Plant extract n.d Decreased NET formation Costa et al. (2016)
6 Myrtaceae Eugenia punicifolia Plant extract n.d Decreased NET formation Costa et al. (2016)

n.d.- not defined.