Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 4;11:638537. doi: 10.3389/fonc.2021.638537

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Qian, Zhou, Xu, Jiang, Chen, Wang, Zuo and Ni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Expression of miR-454-3p correlates with PFS in oxaliplatin treated colorectal cancer patients. (A) Colorectal cancer patients who received oxaliplatin-based chemotherapy were separated into groups based on low or high miR-454-3p expression. Kaplan–Meier survival curves were used to compare the PFS between the two groups. (B) Expression of miR-454-3p in patients who responded to oxaliplatin (n = 25) and who did not respond (n = 20) to oxaliplatin was compared using the two-tailed Student t test. U6 small nuclear RNA was used as an internal control. (C) ROC curve for patients responding vs. non-responding to oxaliplatin treatment. The AUC value was 0.723, yielding sensitivity of 71.0% and specificity of 73.2% at the cutoff value of 3.1.