TABLE 1.
The 17 functional categories and their enrichment for either positive or negative main patterns (independent of time breaks).
| Functional category | Positive (1,201) | Negative (3,436) |
| Adhesion, communication, aggregation, migration | 8.05E-25* (225) | 1 (362) |
| Binding | 1.72E-106* (570) | 8.08E-12* (1,145) |
| Biological regulation and behavior | 8.05E-25* (199) | 1 (322) |
| Biosynthesis and catalytical activity | 7.37E-05* (322) | 0.009* (803) |
| Cell cycle, proliferation, growth, and death | 1 (102) | 7.43E-20* (690) |
| Cellular component organization or biogenesis | 1.19E-34* (427) | 3.48E-13* (1,000) |
| Developmental process and reproduction | 0.122 (241) | 0.054 (690) |
| Disease | 1 (77) | 1.38E-12* (464) |
| Environmental information processing, response to stimulus, and signaling | 4.88E-13* (371) | 1 (790) |
| Genetic information process | 1 (225) | 1.26E-83* (1,719) |
| Immune system | 1 (83) | 7.44E-06* (372) |
| Localization and transport | 4.11E-36* (365) | 1 (479) |
| Membrane | 2.19E-96* (476) | 0.434 (747) |
| Metabolism | 0.129 (356) | 2.45E-08* (1,118) |
| Organelle | 2.38E-70* (269) | 1.11E-04* (450) |
| System process | 3.20E-42* (168) | 1 (130) |
| Unclassified | 4.12E-44* (81) | 1 (68) |
Enrichment p-values are listed and marked significant (∗) for p < 0.05. The number of genes belonging to each category is reported in parentheses.